Edit: I'm currently printing an update I did on the frame so no support is needed. I'll upload that file if it comes out right

This is my frame design I made to house my lithophane I made of my wife and I on our wedding day 8 years ago. This was my gift to my wife. The frame is printed with only supports on the inside (may not need it if bridging dialed in correctly) 

Material: PLA American filament classic lithophane white AF

Printer: Anycubic Kobra 

Settings:

I used the website lithophanemaker.com for the lithophane and adjusted my settings there as well as in cura 5.2.1 (I'll cover that one in a bit) 

Resolution: 0.15

Width: 200mm

Height: 133mm

Depth: 5mm

Base Height: 5mm

Overhangs angle: 60⁰

Max thickness: 3mm

Min thickness: 0.6mm

Adjust crop accordingly to your photo

Cura settings: 

Height:  0.15

Wall: 7

Infill: can be zeroed out but I left it at 15%. Wall amount won't allow for infill

Hot end: 205⁰

Buildplate: 60⁰

Speed:  45mm/s

Outer wall speed: 30mm/s

Inner wall speed: 30mm/s

Top/ bottom speed:  25mm/s

Travel speed:  80mm/s

Initial layer print speed:  15mm/s

Initial layer travel speed: 45mm/s

Brim: 8 line count

In cura you can save these settings as a new profile by opening your profile setting and selecting "create profile from current settings/overides and naming it lithophane profile. This way you don't have to remember what you changed. Just select the litho profile and done. 

Frame for lithophane sized to fit 133/H x 200/W

Material: PLA Geeetech Matte black 205⁰

Nothing special here just 0.2 layer Height

Printed at 80mm/s with 15⁰ gyroid Infill