This is a Print in Place Toothpaste squeezer.  Print standing up and make sure to print with 100% infill at least near the top where the two parts connect.  You will need good layer adhesion in this part as well.  I have printed off a handful for my family to use and none have broken off yet, but we don't torque them too hard.

You may have to fold over the end of the toothpaste tube when inserting to get it to not slip out when squeezing.

I have tested on regular sized toothpaste, kids size, lotion tubes, and some topical medicines as well.